Biography

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My research activities have centred upon the developmental origins of health and disease (DOHaD).  Increasing evidence supports the DOHaD hypothesis which argues for a causal relationship between early life events (i.e. environmental factors) and increased disease risk in later life.  Currently, the mechanisms behind these observed relationships are poorly understood. 

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My research programme explores the DOHaD hypothesis in the context of childhood cancers and aims to uncover the molecular mechanisms linking early life exposures associated with increased risk. This includes studies investigating the impact of environmental factors on epigenetic and genetic events associated with childhood cancers.  The objective of this research is to aid understanding of the causes of childhood cancer, provide predictive disease biomarkers and help inform potential public health preventative strategies.

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Memberships

United Kingdom Environmental Mutagen Society (UKEMS)
Children’s Cancer and Leukaemia Group (CCLG)
European Nutrigenomics Organisation (NuGO)

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